Table 1 The results of prediction servers on protein stability due to three novel deleterious variants
Stability prediction server | INPS-3D | mCSM | SAAFEC-SEQ | I-Mutant2.0 |
|---|---|---|---|---|
GLRA2: (p.Arg350Cys) | Destabilizing | Destabilizing | Destabilizing | Decreased stability |
ZDHHC9: (p.Leu189Pro) | Destabilizing | Destabilizing | Destabilizing | Decreased stability |
ATP2B3: (p.Asp847Glu) | Destabilizing | Destabilizing | Destabilizing | Decreased stability |