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Table 3 Distribution of HLA-DRB1*11/12 genotypes in the study population

From: Association of HLA-DRB1*11 and HLA-DRB1*12 gene polymorphism with COVID-19 in Burkina Faso

Clinical status

Genotypes HLA-DRB1*11/12

   

+/+

+/-

-/+

-/-

p-value

OR

95% CI

CC- (n = 48)

2 (4.2)

2 (4.2)

1 (2.1)

43 (89.6)

0.651a

1.971

[0.312–12.444]

CC+ (n = 38)

3 (7.9)

10 (26.3)

5 (13.2)

20 (52.6)

0.725b

1.533

[0.307–7.665]

SC+ (n = 52)

6 (11.5)

3 (5.8)

3 (5.8)

40 (76.9)

0.728c

1.522

[0.356–6.513]

NC+ (n = 60)

1 (1.7)

11 (18.3)

8 (13.3)

40 (66.7)

0.296d

0.198

[0.020–1.975]

Total (n = 198)

12 (6.1)

26 (13.1)

17 (8.6)

143 (72.2)

0.048e

7.695

[0.895–66.189]

  1. Legend: CC-: Negative cases; CC+: asymptomatic positive case; NC+: symptomatic positive case; SC+: severe positive cases. Comparison for HLA-DRB1*11/12 genotype +/+a: CC- vs. CC+; b: CC- vs. (SC+ & NC+); c: CC + vs. SC+; d: CC + vs. NC+; e: SC + vs. NC+.