Genetic polymorphisms of GGT1 gene (rs8135987, rs5751901 and rs2017869) are associated with neoadjuvant chemotherapy efficacy and toxicities in breast cancer patients

Table 1 Genotype distribution and HWE

Gene	SNP	SNP location	Major allele	Minor allele	Genotype Distribution ^A N (%)	MAF	HWE
*GGT1* gene	rs8135987	chr22: 25,012,854	T	C	69(48.3)/58(40.5)/16(11.2)	0.303	0.1546
	rs5751901	chr22: 24,992,266	T	C	57(39.9)/62(43.3)/24(16.8)	0.344	0.1029
	rs2017869	chr22: 24,997,309	G	C	59(41.3)/61(42.6)/23(16.1)	0.353	0.0687

HWE Hardy–Weinberg equilibrium, MAF minor allele frequency (Southern Han Chinese and Han Chinese in Beijing)
^A The order of genotype is wild homozygote/heterozygote/mutant homozygote

ISSN: 1755-8794