Skip to main content

Table 2 Clinic-pathological characteristics of the study population

From: Genetic polymorphisms of GGT1 gene (rs8135987, rs5751901 and rs2017869) are associated with neoadjuvant chemotherapy efficacy and toxicities in breast cancer patients

Patient characteristics

N(%)

Age at first diagnosis (years)

  ≤ 50

61 (42.66)

  > 50

82 (57.34)

Menses

 Premenopausal

59(41.26)

 Postmenopausal

84(58.74)

Body Mass Index (BMI)

  ≤ 23

69(48.25)

  > 23

74(51.75)

Estrogen Receptor (ER) (%)

  < 10

50(34.97)

  ≥ 10

93(65.03)

Progesterone Receptor (PR) (%)

  < 10

42(29.37)

  ≥ 10

101(70.63)

Ki-67 (%)

  < 30

35(24.48)

  ≥ 30 & < 60

65(45.45)

  ≥ 60

43(30.07)

HER-2 statusA

 Negative

84(58.74)

 Positive

59(41.26)

Clinical Tumor stageB

 cT1-cT2

72(50.35)

 cT3-cT4

71(49.65)

Clinical Nodal statusB

 cN0

19(13.29)

 cN1-3

124(86.71)

Efficacy

 Non-pCR

93(65.03)

 pCR

50(34.97)

  1. AHER-2 positive was defined as IHC staining 3 + or FISH (florescent in situ hybridization) showing HER2 gene amplification
  2. BThe clinical staging was based on the eighth edition of American Joint Committee on Cancer (AJCC) TNM classification. The clinical stage of the patient was determined by CT, MRI and bone scan before treatment. Fine needle or core needle biopsy was performed for clinically significant enlarged lymph nodes