Table 3 Association between selected SNPs and pCR

Genotype Distribution

 rs8135987 (T > C)

  TT

30(60.0)

39(41.9)

-

-

-

-

  TC

16(32.0)

42(45.2)

3.450

0.063

0.033

0.30(0.09–0.90)

  CC

4(8.0)

12(12.9)

1.848

0.258

0.976

1.03(0.14–7.14)

  TT

30(60.0)

39(41.9)

-

-

-

-

  TC + CC

20(40.0)

54(58.1)

4.250

0.039

0.060

0.37(0.13–1.04)

  TT + TC

46(92.0)

81(87.1)

-

-

-

-

  CC

4(8.00)

12(12.9)

0.787

0.422

0.591

1.64(0.26–10.10)

  TT + CC

34(68.0)

51(54.8)

-

-

-

  TC

16(32.0)

42(45.1)

2.336

0.126

0.029

0.30(0.10–0.88)

 Allele

  C

24(24.0)

66(35.5)

-

-

-

-

  T

76(76.0)

120(64.5)

3.977

0.046

-

-

 rs5751901 (T > C)

  TT

21(42.0)

36(38.7)

-

-

-

-

  TC

20(40.0)

42(45.2)

0.276

0.599

0.475

0.68 (0.23–1.95)

  CC

9(18.0)

15(16.1)

0.003

0.955

0.629

1.42 (0.33–5.96)

  TT

21(42.0)

36(38.7)

-

-

-

-

  TC + CC

29(58.0)

57(61.2)

0.147

0.702

0.705

0.83(0.31–2.18)

  TT + TC

41(82.0)

78(83.9)

-

-

-

-

  CC

9(18.0)

15(26.1)

0.081

0.817

0.436

1.67(0.44–6.31)

  TT + CC

30(60.0)

51(54.8)

-

-

-

-

  TC

20(40.0)

42(45.2)

0.352

0.553

0.352

0.62(0.23–1.68)

 Allele

  C

38(38.0)

72(38.7)

-

-

-

-

  T

62(62.0)

114(61.3)

0.138

0.906

-

-

 rs2017869 (G > C)

  GG

21(42.0)

38(40.8)

-

-

-

-

  GC

21(42.0)

40(43.0)

0.018

0.893

0.800

0.87(0.31–2.49)

  CC

8(16.0)

15(16.1)

0.005

1.000

0.616

1.45(0.34–6.23)

  GG

21(42.0)

38(40.9)

-

-

-

-

  GC + CC

29(58.0)

55(59.1)

0.017

0.895

0.998

0.99(0.37–2.61)

  GG + GC

42(84)

78(83.9)

-

-

-

-

  CC

8(16)

15(16.1)

0.000

1.000

0.537

1.50(0.38–6.11)

  GG + CC

29(58.0)

53(57.0)

-

-

-

-

  GC

21(42.0)

40(43.0)

0.014

0.907

0.662

0.80(0.29–2.16)

 Allele

  G

63(63.0)

116(62.4)

-

-

-

-

  C

37(37.0)

70(37.6)

0.011

0.916

-

-

 Haplotype (rs5751901—rs2017869)

  TG

42(58.3)

78(58.2)

0.000

0.984

-

-

  CC

28(38.9)

55(41.0)

0.132

0.717

-

-

  CG

2(2.8)

1(0.8)

0.004

0.952

-

-