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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Comparison of methylation estimates obtained via MinION nanopore sequencing and sanger bisulfite sequencing in the TRPA1 promoter region

Fig. 2

Comparison of methylation data of the TRPA1 promoter obtained via bisulfite and nanopore sequencing. Sanger bisulfite sequencing results were published previously [13, 14], nanopore sequencing using the same DNA samples was conducted in the present study (from healthy controls and Morbus Crohn patients). A: The relationship between data points generated by nanopore and Sanger sequencing is best described by a non-linear curved fit, showing most prominent mismatches in the methylation range between 0 and 20%; B: A Quantile-Quantile (QQ) plot illustrates the fit of the non-linear regression line

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BMC Medical Genomics

ISSN: 1755-8794

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