Lineage Marker | Bovis |
|---|
Accession ID
|
C1427476T
|
A2831482G
|
C3624593T
|
|---|
ERR017796
| ✓ | ✓ | ✓ |
ERR026636
| ✓ | ✓ | ✓ |
ERR046747
| ✓ | ✓ | ✓ |
ERR046748
| ✓ | ✓ | ✓ |
ERR046749
| ✓ | ✓ | ✓ |
ERR046954
| ✓ | ✓ | ✓ |
ERR046961
| ✓ | ✓ | ✓ |
ERR046989
| ✓ | ✓ | ✓ |
ERR387001*
| ✓ | ✓ | ✓ |
SRR16278270 | X | X | X |
- Nine pathogen isolates from humans (underlined) were classified when deposited into NCBI as MTB, but their genotypes by GWAS did not align with other MTB isolates. These isolates were checked for three MBO lineage-determining SNPs as reported by Coll et al. [24], and all 9 were found to possess these SNPs, indicating a misclassification in the database. This was confirmed by SNP-IT [25], which also reported one isolate was a BCG strain (starred). Conversely, one isolate (SRR16278270) was classified as MBO, but was shown not to possess any MBO lineage-determining SNPs, supporting a misclassification of an MTB isolate as MBO
- *BCG strain
