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Table 2 Demographical and clinical characteristics of Ichthyosis vulgaris patients (Total = 35)

From: Filaggrin gene variants among Saudi patients with ichthyosis vulgaris

Demographical characteristics

n (%)

Sex

  

Male

22 (62.86)

Female

13 (37.14)

Age

  

Mean age

21.5 ± 13.3

 

< 10

4 (17.14)

10–20

13 (37.14)

> 20

18 (51.4)

Fitzpatrick skin type

35 (100)

Affected Family Members

32 (91.4%)

Consanguinity of parents

  

First degree

22 (62.8)

Second degree

3 (8.5)

None

10 (28.5)

Fitzpatrick skin type

 

Type 4

35 (100)

Coexisting abnormality

 

Sickle cell anemia

2 (5.7)

Others

2 (5.7)

Pruritus

14 (40)

Allergic rhinitis

1 (2.9)

Other allergies

1 (2.9)

Oral retinoids

 

Acitretin

3 (8.6)

Oral retinoid dose per day

 

5–10 mg

2 (66.7)

21–30 mg

1 (33.3)

Oral retinoids duration

 

1–3 months

1 (33.3)

3–4 years

2 (66.7)

Topical therapy

 

Moisturizing

33 (94.3)

Keratolytic and moisturizing

1 (2.9)

Skin dryness

 

Mild

20 (57.1)

Moderate

15 (42.9)

Scaling

 

Mild

25 (71.4)

Moderate

10 (28.6)

Scaling scales

 

Fine

29 (82.9)

Coarse and large

6 (17.1)

Scaling color of scales

 

Light brown

26 (74.3)

Brown

3 (8.6)

White

6 (17.1)

Scaling site of scaling

 

Neck, trunk, or extremities

35 (100)

Sparing flexures

20 (57.1)

Keratosis pilaris

1 (2.9)

Hyperkeratosis

 

Plantar

18 (51.4)

Palmoplantar

4 (11.4)

Palmar hyperlinearity

28 (80)

Teeth

 

Caries

9 (25.7)

Abnormal occlusion and caries

2 (5.7)

Abnormal occlusion

1 (2.9)

Abnormal occlusion, caries, and discoloration

1 (2.9)

Caries and discoloration

1 (2.9)

Saliva collection

35 (100)

FLGVariant

22