From: Filaggrin gene variants among Saudi patients with ichthyosis vulgaris
Demographical characteristics | n (%) | |
---|---|---|
Sex | Â | Â |
Male | 22 (62.86) | |
Female | 13 (37.14) | |
Age | Â | Â |
Mean age | 21.5 ± 13.3 |  |
< 10 | 4 (17.14) | |
10–20 | 13 (37.14) | |
> 20 | 18 (51.4) | |
Fitzpatrick skin type | 35 (100) | |
Affected Family Members | 32 (91.4%) | |
Consanguinity of parents | Â | Â |
First degree | 22 (62.8) | |
Second degree | 3 (8.5) | |
None | 10 (28.5) | |
Fitzpatrick skin type | Â | |
Type 4 | 35 (100) | |
Coexisting abnormality | Â | |
Sickle cell anemia | 2 (5.7) | |
Others | 2 (5.7) | |
Pruritus | 14 (40) | |
Allergic rhinitis | 1 (2.9) | |
Other allergies | 1 (2.9) | |
Oral retinoids | Â | |
Acitretin | 3 (8.6) | |
Oral retinoid dose per day | Â | |
5–10 mg | 2 (66.7) | |
21–30 mg | 1 (33.3) | |
Oral retinoids duration | Â | |
1–3 months | 1 (33.3) | |
3–4 years | 2 (66.7) | |
Topical therapy | Â | |
Moisturizing | 33 (94.3) | |
Keratolytic and moisturizing | 1 (2.9) | |
Skin dryness | Â | |
Mild | 20 (57.1) | |
Moderate | 15 (42.9) | |
Scaling | Â | |
Mild | 25 (71.4) | |
Moderate | 10 (28.6) | |
Scaling scales | Â | |
Fine | 29 (82.9) | |
Coarse and large | 6 (17.1) | |
Scaling color of scales | Â | |
Light brown | 26 (74.3) | |
Brown | 3 (8.6) | |
White | 6 (17.1) | |
Scaling site of scaling | Â | |
Neck, trunk, or extremities | 35 (100) | |
Sparing flexures | 20 (57.1) | |
Keratosis pilaris | 1 (2.9) | |
Hyperkeratosis | Â | |
Plantar | 18 (51.4) | |
Palmoplantar | 4 (11.4) | |
Palmar hyperlinearity | 28 (80) | |
Teeth | Â | |
Caries | 9 (25.7) | |
Abnormal occlusion and caries | 2 (5.7) | |
Abnormal occlusion | 1 (2.9) | |
Abnormal occlusion, caries, and discoloration | 1 (2.9) | |
Caries and discoloration | 1 (2.9) | |
Saliva collection | 35 (100) | |
FLGVariant | 22 |