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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Identifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA

Fig. 5

Identification of modules associated with IgAN subtypes, the functional enrichment of the module and scatter plot of the hub genes in the module. (A) Module-subtype correlation heat map. Rows correspond to modules, while columns correspond to subtypes, where subtype I, subtype II, and subtype III indicate viral hormonal, mixed, and bacterial immunotypes, respectively. Correlation values and P-values are shown in cells. Those in parentheses indicate P-values, and those without parentheses indicate correlation values, with red indicating a positive correlation and green indicating a negative correlation. (B) Biological process analysis of modules. (C) Molecular function analysis of modules. (D) Pathway enrichment analysis of cyan, light green, and yellow modules. Scatter plots of gene significance for IgAN subtype (GS) versus module members (MM) in (E) cyan module, (F) light green module, and (G) yellow module, correlation coefficients, and P-values are listed above the scatter plots, red indicates hub genes in each module.

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BMC Medical Genomics

ISSN: 1755-8794

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