BMC Medical Genomics

Table 1 Subtype-specific genes and their significance with clinical features

From: Identifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA

genesymbol	subtype1	subtype2	subtype3	proteinuria	eGFR
NR4A1	+			*	*
ATF3	+			*	NA
FOSB	+			NA	NA
ARC	+			NA	NA
JUN	+			*	*
NR4A3	+			NA	NA
CCL3L3	+			NA	NA
NR4A2	+			NA	*
ZFP36	+			NA	*
SLC4A2	+			NA	*
POU5F1	+			NA	NA
TSC22D4	+			NA	*
RASD1	+			*	*
SNORA56	+			NA	NA
FOS	+	+		*	*
SLC2A3	+	+	+	*	NA
FNTB		+	+	NA	NA
TRIB1	+	+		NA	*
TUBB3		+	+	NA	*
LIF			+	NA	*
FOXE1			+	NA	NA
SLPI			+	NA	*
C19orf51			+	*	NA

Note: We use “+” to indicate that the gene is subtype-specific, “-” to suggest that the gene is not subtype-specific, “*” to indicate that the gene is significantly associated with clinical features, and "NA" to indicate that there are no corresponding clinical data.

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ISSN: 1755-8794

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