Fig. 1

The AS analysis of cardiac tissues in MIRI. (A) PCA based on ratio values of all RASEs’ different expression levels. (B) Bar plot showing the RASEs. (C) Hierarchical clustering heatmap of the RASEs based on ratio values. (D) Scatter plot shows the top ten GO BP results of the RASGs. (E) Scatter plot shows the top ten KEGG pathways of the RASGs. (F) Bar plot shows the statistical differences and expression patterns of some important genes’ RASEs from RT-qPCR and RNA-seq validation. The Y-axis represent the AS ratio between model event and alternative event. Mean ± SEM is represented by error bars. Student’s t-test; *** P-value < 0.001, ** P-value < 0.01, * P-value < 0.05