Table 4 Colocalization analysis results for exposures instrumented through only one SNP
From: A phenome-wide approach to identify causal risk factors for deep vein thrombosis
Analysis type | Exposure | nr SNP* | PP.H0 | PP.H1 | PP.H2 | PP.H3 | PP.H4 |
|---|---|---|---|---|---|---|---|
BMI-associated proteins | Plasminogen activator inhibitor 1 | 2604 | 3.0254E-13 | 1.9614E-06 | 3.9637E-09 | 0.02472248 | 0.97527556 |
Neurogenic locus notch homolog protein 1 | 3856 | 1.0694E-79 | 4.778E-73 | 2.2382E-07 | 0.99999972 | 6.0801E-08 | |
Inhibin beta C chain | 4079 | 1.1109E-29 | 2.6137E-23 | 4.2502E-07 | 0.99999948 | 9.3591E-08 | |
MR-PheWAS | Lysine | 547 | 2.4588E-11 | 0.98338278 | 3.2772E-13 | 0.01310352 | 0.0035137 |
Bipolar disorder / mania | 3533 | 0.47264348 | 0.43702738 | 0.03965284 | 0.03665077 | 0.01402554 | |
Chronic obstructive pulmonary disorder | 4229 | 0.0766326 | 0.83975957 | 0.00333097 | 0.03645779 | 0.04381907 | |
X-14473 | 655 | 6.292E-07 | 0.83967623 | 6.959E-08 | 0.09280245 | 0.06752062 | |
Docosapentaenoate | 614 | 1.9077E-08 | 0.62830917 | 1.1181E-09 | 0.03649044 | 0.33520037 | |
Adrenate | 626 | 1.8886E-18 | 0.5838098 | 1.1167E-19 | 0.03413747 | 0.38205274 | |
Stearidonate | 674 | 5.34E-11 | 0.50441818 | 3.2335E-12 | 0.03007888 | 0.46550294 | |
Eicosapentanoate | 633 | 2.8064E-17 | 0.22721212 | 1.6606E-18 | 0.01268473 | 0.76010315 | |
Arachidonate | 626 | 4.9721E-77 | 0.17796851 | 2.9399E-78 | 0.00971061 | 0.81232088 |