Table 1 Associations of IL-17 levels with rheumatoid arthritis in MR with IVW, MR-Egger, WM method

IL-17A

12

IVW

1.095

0.990, 1.210

0.078

0.701

0.013*

MR-Egger

0.844

0.540, 1.320

0.475

0.747

0.079

WM

1.135

0.994, 1.297

0.063

-

0.011*

IL-17RA

6

IVW

1.113

1.006, 1.231

0.038

0.763

0.006*

MR-Egger

1.209

0.934, 1.564

0.223

0.714

0.037*

WM

1.142

1.008, 1.293

0.034

-

0.006*

IL-17C

9

IVW

1.007

0.890, 1.139

0.910

0.594

0.152

MR-Egger

1.139

0.884, 1.468

0.348

0.625

0.058

WM

1.073

0.908, 1.268

0.414

-

0.069

IL-17RC

13

IVW

1.006

0.904, 1.119

0.913

0.084

0.152

MR-Egger

1.095

0.703, 1.706

0.696

0.063

0.116

WM

0.934

0.822, 1.061

0.283

-

0.047*

IL-17D

10

IVW

0.979

0.843, 1.137

0.778

0.189

0.130

MR-Egger

0.882

0.599, 1.300

0.545

0.154

0.091

WM

0.981

0.812, 1.184

0.842

-

0.140

IL-17RD

11

IVW

0.983

0.876, 1.104

0.773

0.61

0.129

MR-Egger

0.903

0.583, 1.396

0.656

0.53

0.109

WM

0.949

0.812, 1.109

0.526

-

0.088