Table 2 The associations of IL-17 cytokines with RA in multivariable MR with inverse-variance weighted method
From: Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis
Exposure | Outcome | nSNP | Beta | SE | OR (95%CI) | P-value | P.adj |
|---|---|---|---|---|---|---|---|
IL17A | RA | 52 | 0.041 | 0.062 | 1.064(1.011–1.118) | 0.515 | 0.086 |
IL17C | RA | 52 | 0.047 | 0.067 | 1.069(1.016–1.122) | 0.481 | 0.080 |
IL17D | RA | 52 | -0.047 | 0.064 | 1.066(1.012–1.119) | 0.456 | 0.076 |
IL17RA | RA | 52 | 0.083 | 0.048 | 1.049(0.997–1.102) | 0.083 | 0.014* |
IL17RC | RA | 52 | -0.039 | 0.053 | 1.054(1.001–1.107) | 0.460 | 0.077 |
IL17RD | RA | 52 | -0.019 | 0.039 | 1.040(0.988–1.092) | 0.624 | 0.104 |