Screening of key genes in the pathogenesis of muscle atrophy in CKD-PEW children based on RNA sequencing

BMC Medical Genomics

Table 1 Signaling pathways involved after screening

ID	Description	Gene Ratio	Bg Ratio	p value	p.adjust	q value	Count
hsa 05022	Pathways of neurodegeneration-multiple diseases	287/3603	475/8102	4.63E-13	6.61E-11	4.84E-11	287
hsa 04066	H IF-1signalng pathway	67/3603	109/8102	0.000242821	0.003063286	0.002241429	67
hsa 04662	Bc ll receptor signaling pathway	52/3603	82/8102	0.00040248	0.003945969	0.002887294	52
hsa 04919	Thyroid hormone signaling pathway	72/3603	121/8102	0.000576795	0.005266009	0.003853177	72
hsa 05235	PD-L 1 expression and PD-1 checkpoint pathway in cancer	55/3603	89/8102	0.0007067	0.006264796	0.004583997	55
hsa 04722	Neurotrophin signaling pathway	69/3603	119/8102	0.001954049	0.015260194	0.011165996	69
hsa 03460	Fanconi anemia pathway	34/3603	54/8102	0.004654828	0.027263995	0.019949265	34
hsa 04370	VEGF signaling pathway	36/3603	59/8102	0.007576716	0.040083273	0.029329224	36
hsa 04115	p 53 signaling pathway	43/3603	73/8102	0.008963409	0.043880568	0.032107733	43
hsa 04910	Insulin signaling pathway	75/3603	137/8102	0.009480865	0.045731233	0.033461878	75

ISSN: 1755-8794