Table 1 The most significant KEGG pathways based on P-value*
ID | Description | Count | P-value | geneID |
|---|---|---|---|---|
hsa04974 | Protein digestion and absorption | 10 | 5.45E-07 | COL18A1, SLC7A8, CPA2, COL10A1, COL8A1, COL6A3, COL5A2, COL4A1, COL1A2, COL1A1 |
hsa04971 | Gastric acid secretion | 8 | 4.28E-06 | KCNE2, SST, KCNJ16, CHRM3, CCKBR, CA2, ATP4B, ATP4A |
hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 8 | 5.21E-06 | SULT2A1, GSTA1, CYP3A5, ALDH3A1, ADH7, ADH1C, ADH1A, AKR7A3 |
hsa04512 | ECM-receptor interaction | 8 | 1.29E-05 | THBS4, THBS2, SPP1, ITGA5, COL6A3, COL4A1, COL1A2, COL1A1 |
hsa00982 | Drug metabolism - cytochrome P450 | 7 | 2.97E-05 | MAOA, GSTA1, CYP3A5, ALDH3A1, ADH7, ADH1C, ADH1A |
hsa00350 | Tyrosine metabolism | 5 | 7.73E-05 | MAOA, ALDH3A1, ADH7, ADH1C, ADH1A |
hsa00010 | Glycolysis | 6 | 0.003719 | FBP2, ALDOB, ALDH3A1, ADH7, ADH1C, ADH1A |
hsa00830 | Retinol metabolism | 6 | 0.000194 | CYP3A5, CYP2C18, ALDH1A1, ADH7, ADH1C, ADH1A |
hsa05204 | Chemical carcinogenesis - DNA adducts | 6 | 0.000211 | SULT2A1, PTGS2, GSTA1, AKR1C2, CYP3A5, CYP2C18 |
hsa04972 | Pancreatic secretion | 6 | 0.001697 | SLC12A2, RAB27B, PLA2G2A, CPA2, CHRM3, CA2 |
hsa04510 | Focal adhesion | 8 | 003609401 | THBS4, THBS2, SPP1, ITGA5, COL6A3, COL4A1, COL1A2, COL1A1 |