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Table 4 The most significant MF terms based on P-value*

From: Identification of differentially expressed genes associated with the pathogenesis of gastric cancer by bioinformatics analysis

MF terms

P-value

Count

geneID

extracellular matrix structural constituent conferring tensile strength

7.43E-09

8

COL18A1, COL10A1, COL8A1, COL6A3, COL5A2, COL4A1, COL1A2, COL1A1

oxidoreductase activity, acting on CH-OH group of donors

1.56E-08

12

AKR1B10, AKR7A3, PTGR1, AKR1C3, LIPF, HPGD, AKR1C2, AKR1C4, ALDH3A1, ADH7, ADH1C, ADH1A

extracellular matrix structural constituent

2.52E-08

13

MUC17, CTHRC1, COL18A1, THBS2, MUC6, COL10A1, COL8A1, COL6A3, COL5A2, COL4A1, COL1A2, COL1A1, BGN

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

5.97E-08

11

AKR1B10, AKR7A3, PTGR1, AKR1C3, HPGD, AKR1C2, AKR1C4, ALDH3A1, ADH7, ADH1C, ADH1A

oxidoreductase activity, acting on the aldehyde or oxo group of donors

2.93E-07

7

AKR1B10, AKR1C3, ALDH6A1, AKR1C4, ALDH3A1, ALDH1A1, ADH7

aldo-keto reductase (NADP) activity

4.15E-07

6

AKR1B10, AKR7A3, AKR1C3, AKR1C2, AKR1C4, ALDH3A1

D-threo-aldose 1-dehydrogenase activity

8.19E-07

5

AKR1B10, AKR7A3, AKR1C3, AKR1C2, AKR1C4

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

1.90E-06

6

AKR1B10, AKR1C3, ALDH6A1, AKR1C4, ALDH3A1, ALDH1A1

alcohol dehydrogenase (NADP+) activity

2.44E-06

5

AKR1B10, AKR1C, AKR1C2, AKR1C4, ALDH3A1

alditol:NADP + 1-oxidoreductase activity

4.94E-06

4

AKR1B10, AKR1C3, AKR1C2, AKR1C4

  1. *P-value < 0.05 was considered significant