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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Identification and validation of autophagy-related genes in primary open-angle glaucoma

Fig. 2

Identification of hub genes. A The significant GO terms and KEGG pathways of the DEARGs. B The significant modules of DEARGs through PPI network analysis. The PPI network of DEARGs was analyzed by using the STRING database. Medium confidence was set to 0.4, and species was set to human. Color represents connectivity. The higher the connectivity, the darker the color. UBB, RPL15, HSPA8, RPS5 and PSMC1 were selected as key genes. C, D HSPA8 and RPL15 were identified as the hub genes by external dataset validation

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