Fig. 1

Identification prognostic value of Kla-specific genes. A, Differentially expressed Kla-specific genes (DEKlaGs) in BC, with the cut-off criteria |log2FC|>=1, p-value < 0.05. B, Cox regression model in accordance with DEKlaGs. C, Survival analysis according to risk score calculated by Kla-specific genes expression. D;E, Independent prognostic analysis of risk score. T represents the tumor size in tumor TNM classification, N represents the lymph node metastasis in TNM classification, and M represents distant metastasis in TNM classification. F, Visualization of risk level combined with gene expression. Heatmap represents the prognostic gene expression profiles. Blue stands for low expression, while red stands for high expression. The type means risk level. G, Distribution of each risk score according to Kla-specific genes. Green represents low-risk group, while red represents high-risk group. H, Visualization of survival time and risk score. Patients with high-risk score tend to have shorter survival time. I-M, Survival analysis of prognostic Kla-specific genes. FC, Foldchange