Skip to main content
Fig. 5 | BMC Medical Genomics

Fig. 5

From: Integrated single-cell and bulk RNA sequencing analysis identifies a neoadjuvant chemotherapy-related gene signature for predicting survival and therapy in breast cancer

Fig. 5

The correlation between NAC risk score of patients and characterization of the immune microenvironment. A: Heat plot of the activity of cancer hallmarks in the GSE25055 cohort between high- and low-risk group; B: Spearman correlation between the NAC response-related risk score and the immune score (R = 0.27; p < 0.01); C: Spearman correlation between the NAC response-related risk score and the ESTIMATE score; D: The proportions of differentially infiltrated TME immune cells between the high- and low-risk score groups;

E: Top 6 drugs with the highest positive correlation with risk score; F: Comparison of log2 (IC50) values of the top 6 positively correlated drugs between the high- and low-risk score groups; G: Top 6 drugs with the highest negative correlation with risk score; H: Comparison of log2 (IC50) values of the top 6 negatively correlated drugs between the high- and low-risk score groups

Back to article page