Fig. 4

Basic characteristic difference between FA wild-type and mutant-type groups. We analyzed the differences in the factors, including race, age (a-b), FAB, gender, type (c), and cytogenetic risk (d) between the wild-type (Wt) and overall mutant-type (Mut) of FA pathway genes. The results were visualized using the “plotrix” R package. We also conducted the Wilcox test to analyze the difference in age index, and the results were visualized using the “ggbarplot” function of the “ggpubr” R package (b). We then analyzed the mutation percentages of IDH1, NPM1, CEBPA, and FLT3 between the Wt and Mut groups of FA, and the results were visualized using the “barplot” function (e)