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Fig. 7 | BMC Medical Genomics

Fig. 7

From: Mutation spectrum, expression profiling, and prognosis evaluation of Fanconi anemia signaling pathway genes for 4259 patients with myelodysplastic syndromes or acute myeloid leukemia

Fig. 7

Prognosis evaluation of FA mutation. We utilized the “survival” and “surviviner” packages to assess the OS prognosis of MDS + AML, MDS, and AML patients. The evaluation was conducted for both the wild-type (Wt) and overall mutant-type (Mut) of FA pathway genes (a), as well as for the Wt and Mut groups of FANCA (b), Targeting the factors (TMB, cytogenetic risk, FLT3/NPM1/FA mutation), ROC analyses were performed, and the AUC values for the OS prognosis were calculated for the 1-, 3-, and 5-year survival time points (c)

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BMC Medical Genomics

ISSN: 1755-8794

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