Skip to main content

Table 7 SNP–SNP interaction models analyzed by the MDR method

From: Association of MMP3, MMP14, and MMP25 gene polymorphisms with cerebral stroke risk: a case-control study

Model

Training Bal. Acc

Testing Bal. Acc

OR (95% CI)

p value

CVC

rs679620

0.536

0.520

1.34 (1.08–1.67)

0.0080

9/10

rs679620, rs10431961

0.541

0.508

1.48 (1.16–1.89)

0.0016

4/10

rs679620, rs2236302, rs10431961

0.549

0.503

1.47 (1.19–1.83)

0.0005

9/10

rs679620, rs520540, rs2236302, rs10431961

0.553

0.502

1.52 (1.22–1.90)

0.0002

10/10

  1. MDR, multifactor dimensionality reduction; Bal. Acc., balanced accuracy; CVC, cross-validation consistency; OR, odds ratio; 95% CI, 95% confidence interval;
  2. p values were calculated using χ2 tests; p < 0.05 and bold text indicate statistical significance
Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us