Fig. 5

Function enrichment analysis of IFITs-related gene sets in AML. A We screened out the first 1000 genes positively related to IFIT2/3/5 based on Spearman correlation analysis. The heat maps exhibited the top 20 genes of IFIT2/3/5, respectively. B Identification of the co-correlated genes of IFIT2/3/5 by Venn diagram. C KEGG pathways annotations of IFITs and their co-correlated genes. D The association between IFIT2/3/5 expression and various apoptosis regulators, including caspase7 (CASP7), caspase8 (CASP7), caspase10 (CASP7) and X-linked inhibitor of apoptosis (XIAP)