SNP_ID | Model | Genotypes | Age > 60 | Age ≤ 60 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | OR (95% CI) | p | Case | Control | OR (95% CI) | p | |||
rs1398007 | Co-dominant | CC | 119 | 128 | 1 | 99 | 112 | 1 | ||
CT | 124 | 113 | 1.12(0.78–1.62) | 0.538 | 98 | 95 | 1.18(0.80–1.76) | 0.408 | ||
TT | 22 | 21 | 1.08(0.56–2.10) | 0.812 | 25 | 18 | 1.48(0.75–2.91) | 0.255 | ||
Dominant | CC | 119 | 128 | 1 | 99 | 112 | 1 | |||
CT + TT | 146 | 134 | 1.12(0.79–1.59) | 0.541 | 123 | 113 | 1.23(0.84–1.79) | 0.280 | ||
Recessive | CC + CT | 243 | 241 | 1 | 197 | 207 | 1 | |||
TT | 22 | 21 | 1.02(0.54–1.93) | 0.944 | 25 | 18 | 1.37(0.71–2.62) | 0.344 | ||
Log-additive | — | — | — | 1.08(0.82–1.42) | 0.608 | — | — | 1.20(0.90–1.61) | 0.211 | |
rs13146272 | Co-dominant | CC | 100 | 96 | 1 | 77 | 92 | 1 | ||
CA | 124 | 121 | 0.99(0.68–1.46) | 0.972 | 115 | 104 | 1.31(0.87–1.96) | 0.202 | ||
AA | 40 | 45 | 0.77(0.46–1.30) | 0.323 | 30 | 29 | 1.18(0.65–2.16) | 0.580 | ||
Dominant | CC | 100 | 96 | 1 | 77 | 92 | 1 | |||
CA + AA | 164 | 166 | 0.93(0.65–1.33) | 0.692 | 145 | 133 | 1.28(0.87–1.89) | 0.216 | ||
Recessive | CC + CA | 224 | 217 | 1 | 192 | 196 | 1 | |||
AA | 40 | 45 | 0.77(0.48–1.24) | 0.287 | 30 | 29 | 1.02(0.59–1.77) | 0.946 | ||
Log-additive | — | — | — | 0.90(0.70–1.15) | 0.405 | — | — | 1.14(0.86–1.51) | 0.345 | |
rs3736455 | Co-dominant | TT | 93 | 86 | 1 | 75 | 88 | 1 | ||
TG | 135 | 132 | 0.95(0.65–1.40) | 0.972 | 119 | 108 | 1.27(0.84–1.91) | 0.259 | ||
GG | 37 | 43 | 0.73(0.43–1.25) | 0.251 | 28 | 28 | 1.13(0.61–2.08) | 0.707 | ||
Dominant | TT | 93 | 86 | 1 | 75 | 88 | 1 | |||
TG + GG | 172 | 175 | 0.89(0.62–1.29) | 0.546 | 147 | 136 | 1.24(0.84–1.83) | 0.288 | ||
Recessive | TT + TG | 228 | 218 | 1 | 194 | 196 | 1 | |||
GG | 37 | 43 | 0.75(0.46–1.23) | 0.253 | 28 | 28 | 0.98(0.56–1.73) | 0.945 | ||
Log-additive | — | — | — | 0.87(0.68–1.13) | 0.304 | — | — | 1.11(0.84–1.48) | 0.459 | |
rs1053094 | Co-dominant | TT | 105 | 120 | 1 | 87 | 89 | 1 | ||
TA | 128 | 115 | 1.24(0.86–1.79) | 0.259 | 105 | 110 | 0.93(0.62–1.40) | 0.736 | ||
AA | 32 | 27 | 1.45(0.81–2.60) | 0.217 | 30 | 25 | 1.21(0.65–2.25) | 0.543 | ||
Dominant | TT | 105 | 120 | 1 | 87 | 89 | 1 | |||
TA + AA | 160 | 142 | 1.28(0.90–1.82) | 0.175 | 135 | 135 | 0.98(0.67–1.45) | 0.937 | ||
Recessive | TT + TA | 233 | 235 | 1 | 192 | 199 | 1 | |||
AA | 32 | 27 | 1.30(0.74–2.26) | 0.360 | 30 | 25 | 1.26(0.71–2.24) | 0.437 | ||
Log-additive | — | — | — | 1.22(0.93–1.58) | 0.148 | — | — | 1.05(0.79–1.39) | 0.747 | |
rs56413992 | Co-dominant | CC | 161 | 182 | 1 | 127 | 144 | 1 | ||
CT | 90 | 74 | 1.49(1.02–2.18) | 0.042 | 85 | 70 | 1.33(0.89–1.99) | 0.158 | ||
TT | 14 | 6 | 2.66(0.98–7.21) | 0.054 | 10 | 9 | 1.26(0.49–3.24) | 0.639 | ||
Dominant | CC | 161 | 182 | 1 | 127 | 144 | 1 | |||
CT + TT | 104 | 80 | 1.58(1.09–2.29) | 0.015 | 95 | 79 | 1.33(0.90–1.95) | 0.153 | ||
Recessive | CC + CT | 251 | 256 | 1 | 212 | 214 | 1 | |||
TT | 14 | 6 | 2.35(0.87–6.30) | 0.090 | 10 | 9 | 1.13(0.44–2.88) | 0.803 | ||
Log-additive | — | — | — | 1.54(1.12–2.12) | 0.008 | — | — | 1.25(0.90–1.73) | 0.193 |