SNP_ID | Model | Genotypes | Male | Female | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | OR (95% CI) | p | Case | Control | OR (95% CI) | p | |||
0rs1398007 | Co-dominant | CC | 135 | 159 | 1 | 83 | 81 | 1 | ||
CT | 155 | 146 | 1.25(0.90–1.73) | 0.185 | 67 | 62 | 0.92(0.56–1.51) | 0.748 | ||
TT | 34 | 24 | 1.68(0.94–3.00) | 0.079 | 13 | 15 | 1.01(0.43–2.37) | 0.990 | ||
Dominant | CC | 135 | 159 | 1 | 83 | 81 | 1 | |||
CT + TT | 189 | 170 | 1.31(0.96–1.79) | 0.093 | 80 | 77 | 0.94(0.59–1.49) | 0.784 | ||
Recessive | CC + CT | 290 | 305 | 1 | 150 | 143 | 1 | |||
TT | 34 | 24 | 1.50(0.86–2.61) | 0.150 | 13 | 15 | 1.04(0.45–2.39) | 0.924 | ||
Log-additive | — | — | — | 1.28(1.00–1.63) | 0.052 | — | — | 0.97(0.68–1.39) | 0.864 | |
rs13146272 | Co-dominant | CC | 122 | 127 | 1 | 55 | 61 | 1 | ||
CA | 151 | 155 | 0.98(0.70–1.37) | 0.897 | 88 | 70 | 1.43(0.86–2.38) | 0.173 | ||
AA | 50 | 47 | 1.06(0.66–1.70) | 0.822 | 20 | 27 | 0.70(0.34–1.43) | 0.323 | ||
Dominant | CC | 122 | 127 | 1 | 55 | 61 | 1 | |||
CA + AA | 201 | 202 | 1.00(0.72–1.37) | 0.982 | 108 | 97 | 1.20(0.74–1.95) | 0.452 | ||
Recessive | CC + CA | 273 | 282 | 1 | 143 | 131 | 1 | |||
AA | 50 | 47 | 1.07(0.69–1.66) | 0.764 | 20 | 27 | 0.57(0.29–1.10) | 0.093 | ||
Log-additive | — | — | — | 1.02(0.81–1.27) | 0.890 | — | — | 0.94(0.67–1.32) | 0.724 | |
rs3736455 | Co-dominant | TT | 119 | 118 | 1 | 49 | 56 | 1 | ||
TG | 158 | 164 | 0.91(0.65–1.28) | 0.596 | 96 | 76 | 1.52(0.90–2.54) | 0.116 | ||
GG | 47 | 46 | 0.97(0.60–1.58) | 0.912 | 18 | 25 | 0.73(0.34–1.54) | 0.406 | ||
Dominant | TT | 119 | 118 | 1 | 49 | 56 | 1 | |||
TG + GG | 205 | 210 | 0.93(0.67–1.28) | 0.639 | 114 | 101 | 1.30(0.79–2.13) | 0.296 | ||
Recessive | TT + TG | 277 | 282 | 1 | 145 | 132 | 1 | |||
GG | 47 | 46 | 1.03(0.66–1.60) | 0.910 | 18 | 25 | 0.56(0.28–1.12) | 0.100 | ||
Log-additive | — | — | — | 0.97(0.77–1.22) | 0.784 | — | — | 0.98(0.69–1.39) | 0.905 | |
rs1053094 | Co-dominant | TT | 127 | 141 | 1 | 65 | 68 | 1 | ||
TA | 153 | 156 | 1.09(0.78–1.52) | 0.623 | 80 | 69 | 1.12(0.68–1.84) | 0.661 | ||
AA | 44 | 32 | 1.60(0.95–2.70) | 0.080 | 18 | 20 | 1.00(0.47–2.13) | 0.995 | ||
Dominant | TT | 127 | 141 | 1 | 65 | 68 | 1 | |||
TA + AA | 197 | 188 | 1.17(0.85–1.61) | 0.329 | 98 | 89 | 1.09(0.68–1.75) | 0.716 | ||
Recessive | TT + TA | 280 | 297 | 1 | 145 | 137 | 1 | |||
AA | 44 | 32 | 1.53(0.93–2.50) | 0.092 | 18 | 20 | 0.94(0.46–1.92) | 0.869 | ||
Log-additive | — | — | — | 1.20(0.95–1.52) | 0.124 | — | — | 1.03(0.73–1.46) | 0.851 | |
rs56413992 | Co-dominant | CC | 191 | 222 | 1 | 97 | 104 | 1 | ||
CT | 117 | 98 | 1.37(0.98–1.91) | 0.068 | 58 | 46 | 1.39(0.83–2.30) | 0.209 | ||
TT | 16 | 8 | 2.42(1.00–5.87) | 0.051 | 8 | 7 | 1.35(0.45–4.03) | 0.596 | ||
Dominant | CC | 191 | 222 | 1 | 97 | 104 | 1 | |||
CT + TT | 133 | 106 | 1.44(1.04–2.00) | 0.027 | 66 | 53 | 1.38(0.85–2.24) | 0.193 | ||
Recessive | CC + CT | 308 | 320 | 1 | 155 | 150 | 1 | |||
TT | 16 | 8 | 2.18(0.90–5.25) | 0.083 | 8 | 7 | 1.21(0.41–3.58) | 0.730 | ||
Log-additive | — | — | — | 1.43(1.08–1.90) | 0.013 | — | — | 1.28(0.86–1.91) | 0.230 |