SNP_ID | Model | Genotypes | Smoking-Yes | Smoking-No | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | OR (95% CI) | p | Case | Control | OR (95% CI) | p | |||
rs1398007 | Co-dominant | CC | 107 | 130 | 1 | 111 | 110 | 1 | ||
CT | 120 | 109 | 1.31(0.91–1.90) | 0.150 | 102 | 99 | 1.03(0.69–1.53) | 0.888 | ||
TT | 29 | 20 | 1.86(0.98–3.51) | 0.056 | 18 | 19 | 0.89(0.43–1.82) | 0.748 | ||
Dominant | CC | 107 | 130 | 1 | 111 | 110 | 1 | |||
CT + TT | 149 | 129 | 1.39(0.98–1.98) | 0.065 | 120 | 118 | 1.01(0.69–1.47) | 0.975 | ||
Recessive | CC + CT | 227 | 239 | 1 | 213 | 209 | 1 | |||
TT | 29 | 20 | 1.63(0.88–2.99) | 0.118 | 18 | 19 | 0.88(0.44–1.75) | 0.710 | ||
Log-additive | — | — | — | 1.34(1.02–1.76) | 0.034 | — | — | 0.98(0.73–1.32) | 0.891 | |
rs13146272 | Co-dominant | CC | 93 | 98 | 1 | 84 | 90 | 1 | ||
CA | 127 | 127 | 1.04(0.71–1.52) | 0.846 | 112 | 98 | 1.20(0.79–1.82) | 0.384 | ||
AA | 36 | 34 | 1.05(0.60–1.83) | 0.857 | 34 | 40 | 0.76(0.43–1.34) | 0.348 | ||
Dominant | CC | 93 | 98 | 1 | 84 | 90 | 1 | |||
CA + AA | 163 | 161 | 1.04(0.72–1.50) | 0.826 | 146 | 138 | 1.07(0.72–1.58) | 0.741 | ||
Recessive | CC + CA | 220 | 225 | 1 | 196 | 188 | 1 | |||
AA | 36 | 34 | 1.03(0.62–1.72) | 0.910 | 34 | 40 | 0.69(0.41–1.16) | 0.161 | ||
Log-additive | — | — | — | 1.03(0.79–1.34) | 0.829 | — | — | 0.93(0.71–1.22) | 0.641 | |
rs3736455 | Co-dominant | TT | 91 | 88 | 1 | 77 | 86 | 1 | ||
TG | 131 | 138 | 0.98(0.55–1.73) | 0.941 | 123 | 102 | 1.26(0.83–1.92) | 0.270 | ||
GG | 34 | 32 | 0.91(0.62–1.34) | 0.628 | 31 | 39 | 0.76(0.42–1.35) | 0.344 | ||
Dominant | TT | 91 | 88 | 1 | 77 | 86 | 1 | |||
TG + GG | 165 | 170 | 0.92(0.64–1.33) | 0.669 | 154 | 141 | 1.12(0.75–1.66) | 0.577 | ||
Recessive | TT + TG | 222 | 226 | 1 | 200 | 188 | 1 | |||
GG | 34 | 32 | 1.04(0.61–1.75) | 0.893 | 31 | 39 | 0.66(0.39–1.12) | 0.123 | ||
Log-additive | — | — | — | 0.97(0.74–1.27) | 0.809 | — | — | 0.94(0.71–1.24) | 0.671 | |
rs1053094 | Co-dominant | TT | 98 | 114 | 1 | 94 | 95 | 1 | ||
TA | 127 | 121 | 1.21(0.83–1.75) | 0.328 | 106 | 104 | 1.00(0.66–1.49) | 0.981 | ||
AA | 31 | 23 | 1.61(0.87–2.97) | 0.130 | 31 | 29 | 1.14(0.63–2.06) | 0.675 | ||
Dominant | TT | 98 | 114 | 1 | 94 | 95 | 1 | |||
TA + AA | 158 | 144 | 1.27(0.89–1.81) | 0.194 | 137 | 133 | 1.03(0.70–1.50) | 0.899 | ||
Recessive | TT + TA | 225 | 235 | 1 | 200 | 199 | 1 | |||
AA | 31 | 23 | 1.45(0.81–2.59) | 0.207 | 31 | 29 | 1.14(0.65–1.99) | 0.647 | ||
Log-additive | — | — | — | 1.25(0.95–1.63) | 0.115 | — | — | 1.05(0.79–1.38) | 0.750 | |
rs56413992 | Co-dominant | CC | 145 | 171 | 1 | 143 | 155 | 1 | ||
CT | 100 | 83 | 1.44(0.99–2.08) | 0.056 | 75 | 61 | 1.38(0.91–2.10) | 0.133 | ||
TT | 11 | 5 | 2.88(0.96–8.69) | 0.060 | 13 | 10 | 1.39(0.58–3.34) | 0.465 | ||
Dominant | CC | 145 | 171 | 1 | 143 | 155 | 1 | |||
CT + TT | 111 | 88 | 1.51(1.05–2.17) | 0.025 | 88 | 71 | 1.38(0.93–2.05) | 0.112 | ||
Recessive | CC + CT | 245 | 254 | 1 | 218 | 216 | 1 | |||
TT | 11 | 5 | 2.52(0.84–7.52) | 0.098 | 13 | 10 | 1.26(0.53–3.00) | 0.607 | ||
Log-additive | — | — | — | 1.51(1.09–2.08) | 0.012 | — | — | 1.28(0.92–1.78) | 0.137 |