SNP_ID | Model | Genotypes | Drinking-Yes | Drinking-No | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | OR (95% CI) | p | Case | Control | OR (95% CI) | p | |||
rs1398007 | Co-dominant | CC | 67 | 106 | 1 | 151 | 134 | 1 | ||
CT | 93 | 81 | 1.80(1.17–2.78) | 0.008 | 129 | 127 | 0.83(0.59–1.18) | 0.301 | ||
TT | 20 | 13 | 2.41(1.11–5.25) | 0.026 | 27 | 26 | 0.89(0.49–1.61) | 0.698 | ||
Dominant | CC | 67 | 106 | 1 | 151 | 134 | 1 | |||
CT + TT | 113 | 94 | 1.88(1.24–2.86) | 0.003 | 156 | 153 | 0.84(0.61–1.17) | 0.309 | ||
Recessive | CC + CT | 160 | 187 | 1 | 280 | 261 | 1 | |||
TT | 20 | 13 | 1.79(0.85–3.77) | 0.124 | 27 | 26 | 0.97(0.55–1.72) | 0.914 | ||
Log-additive | — | — | — | 1.65(1.19–2.30) | 0.003 | — | — | 0.90(0.70–1.16) | 0.404 | |
rs13146272 | Co-dominant | CC | 76 | 73 | 1 | 101 | 115 | 1 | ||
CA | 86 | 98 | 0.83(0.53–1.29) | 0.400 | 153 | 127 | 1.46(1.01–2.09) | 0.042 | ||
AA | 18 | 29 | 0.58(0.29–1.14) | 0.116 | 52 | 45 | 1.26(0.77–2.05) | 0.354 | ||
Dominant | CC | 76 | 73 | 1 | 101 | 115 | 1 | |||
CA + AA | 104 | 127 | 0.77(0.51–1.17) | 0.224 | 205 | 172 | 1.40(1.00–1.97) | 0.052 | ||
Recessive | CC + CA | 162 | 171 | 1 | 254 | 242 | 1 | |||
AA | 18 | 29 | 0.64(0.34–1.21) | 0.174 | 52 | 45 | 1.02(0.66–1.59) | 0.920 | ||
Log-additive | — | — | — | 0.78(0.57–1.07) | 0.118 | — | — | 1.18(0.93–1.49) | 0.163 | |
rs3736455 | Co-dominant | TT | 74 | 69 | 1 | 94 | 105 | 1 | ||
TG | 89 | 101 | 0.81(0.52–1.25) | 0.337 | 165 | 139 | 1.41(0.98–2.02) | 0.066 | ||
GG | 17 | 29 | 0.54(0.27–1.07) | 0.078 | 48 | 42 | 1.23(0.74–2.04) | 0.425 | ||
Dominant | TT | 74 | 69 | 1 | 94 | 105 | 1 | |||
TG + GG | 106 | 130 | 0.75(0.49–1.14) | 0.174 | 213 | 181 | 1.36(0.96–1.93) | 0.080 | ||
Recessive | TT + TG | 163 | 170 | 1 | 259 | 244 | 1 | |||
GG | 17 | 29 | 0.61(0.32–1.16) | 0.130 | 48 | 42 | 1.00(0.64–1.58) | 0.990 | ||
Log-additive | — | — | — | 0.75(0.55–1.03) | 0.079 | — | — | 1.17(0.91–1.49) | 0.216 | |
rs1053094 | Co-dominant | TT | 65 | 88 | 1 | 127 | 121 | 1 | ||
TA | 92 | 95 | 1.24(0.80–1.93) | 0.332 | 141 | 130 | 1.01(0.71–1.42) | 0.977 | ||
AA | 23 | 17 | 2.04(0.99–4.20) | 0.055 | 39 | 35 | 1.11(0.66–1.88) | 0.701 | ||
Dominant | TT | 65 | 88 | 1 | 127 | 121 | 1 | |||
TA + AA | 115 | 112 | 1.36(0.89–2.06) | 0.156 | 180 | 165 | 1.03(0.74–1.43) | 0.877 | ||
Recessive | TT + TA | 157 | 183 | 1 | 268 | 251 | 1 | |||
AA | 23 | 17 | 1.81(0.91–3.60) | 0.090 | 39 | 35 | 1.11(0.67–1.81) | 0.690 | ||
Log-additive | — | — | — | 1.36(0.99–1.87) | 0.061 | — | — | 1.04(0.82–1.32) | 0.758 | |
rs56413992 | Co-dominant | CC | 94 | 143 | 1 | 194 | 183 | 1 | ||
CT | 80 | 53 | 2.26(1.45–3.51) | < 0.001 | 95 | 91 | 1.04(0.73–1.48) | 0.846 | ||
TT | 6 | 4 | 2.66(0.70–10.10) | 0.150 | 18 | 11 | 1.59(0.73–3.49) | 0.245 | ||
Dominant | CC | 94 | 143 | 1 | 194 | 183 | 1 | |||
CT + TT | 86 | 57 | 2.29(1.48–3.52) | < 0.001 | 113 | 102 | 1.10(0.78–1.54) | 0.593 | ||
Recessive | CC + CT | 174 | 196 | 1 | 289 | 274 | 1 | |||
TT | 6 | 4 | 2.00(0.53–7.52) | 0.305 | 18 | 11 | 1.57(0.72–3.42) | 0.252 | ||
Log-additive | — | — | — | 2.07(1.40–3.06) | < 0.001 | — | — | 1.13(0.86–1.50) | 0.386 |