SNP_ID | Model | Genotypes | Case (With DM) | Controls (Without DM) | OR (95% CI) | p | Case (With HTN) | Controls (Without HTN) | OR (95% CI) | p |
---|---|---|---|---|---|---|---|---|---|---|
rs1398007 | Co-dominant | CC | 62 | 156 | 1 | 150 | 68 | 1 | ||
CT | 63 | 159 | 1.03(0.67–1.57) | 0.908 | 122 | 100 | 0.57(0.38–0.84) | 0.005 | ||
TT | 18 | 29 | 1.64(0.894–3.21) | 0.147 | 31 | 16 | 0.90(0.46–1.78) | 0.764 | ||
Dominant | CC | 62 | 156 | 1 | 150 | 68 | 1 | |||
CT + TT | 81 | 188 | 1.12(0.75–1.67) | 0.586 | 153 | 116 | 0.61(0.42–0.90) | 0.012 | ||
Recessive | CC + CT | 125 | 315 | 1 | 272 | 168 | 1 | |||
TT | 18 | 29 | 1.62(0.86–3.05) | 0.135 | 31 | 16 | 1.22(0.64–2.33) | 0.524 | ||
Log-additive | — | — | — | 1.19(0.88–1.61) | 0.269 | — | — | 0.79(0.59–1.05) | 0.102 | |
rs13146272 | Co-dominant | CC | 59 | 118 | 1 | 111 | 66 | 1 | ||
CA | 59 | 180 | 0.65(0.42–1.01) | 0.057 | 149 | 90 | 0.96(0.64–1.46) | 0.862 | ||
AA | 25 | 45 | 1.05(0.58–1.90) | 0.870 | 43 | 21 | 0.87(0.49–1.57) | 0.651 | ||
Dominant | CC | 59 | 118 | 1 | 111 | 66 | 1 | |||
CA + AA | 84 | 225 | 0.74(0.49–1.11) | 0.140 | 192 | 117 | 0.94(0.64–1.40) | 0.768 | ||
Recessive | CC + CA | 118 | 298 | 1 | 260 | 156 | 1 | |||
AA | 25 | 45 | 1.33(0.77–2.28) | 0.304 | 43 | 27 | 0.89(0.52–1.52) | 0.676 | ||
Log-additive | — | — | — | 0.93(0.69–1.24) | 0.612 | — | — | 0.94(0.71–1.24) | 0.670 | |
rs3736455 | Co-dominant | TT | 56 | 112 | 1 | 106 | 62 | 1 | ||
TG | 62 | 192 | 0.63(0.41–0.97) | 0.037 | 155 | 99 | 0.87(0.57–1.31) | 0.494 | ||
GG | 25 | 40 | 1.18(0.64–2.16) | 0.593 | 42 | 23 | 0.98(0.53–1.81) | 0.956 | ||
Dominant | TT | 56 | 112 | 1 | 106 | 62 | 1 | |||
TG + GG | 87 | 232 | 0.72(0.48–1.10) | 0.126 | 197 | 122 | 0.89(0.60–1.32) | 0.558 | ||
Recessive | TT + TG | 118 | 304 | 1 | 261 | 161 | 1 | |||
GG | 25 | 40 | 1.55(0.89–2.68) | 0.122 | 42 | 23 | 1.07(0.61–1.87) | 0.805 | ||
Log-additive | — | — | — | 0.96(0.71–1.29) | 0.771 | — | — | 0.96(0.72–1.27) | 0.768 | |
rs1053094 | Co-dominant | TT | 69 | 123 | 1 | 122 | 70 | 1 | ||
TA | 61 | 172 | 0.63(0.42–0.96) | 0.032 | 144 | 89 | 0.92(0.61–1.38) | 0.687 | ||
AA | 13 | 49 | 0.48(0.24–0.94) | 0.033 | 37 | 25 | 0.88(0.49–1.60) | 0.685 | ||
Dominant | TT | 69 | 123 | 1 | 122 | 70 | 1 | |||
TA + AA | 74 | 221 | 0.60(0.40–0.89) | 0.011 | 181 | 144 | 0.91(0.62–1.34) | 0.640 | ||
Recessive | TT + TA | 130 | 295 | 1 | 266 | 159 | 1 | |||
AA | 13 | 49 | 0.60(0.32–1.16) | 0.129 | 27 | 25 | 0.92(0.53–1.61) | 0.782 | ||
Log-additive | — | — | — | 0.67(0.49–0.91) | 0.010 | — | — | 0.93(0.71–1.23) | 0.633 | |
rs56413992 | Co-dominant | CC | 90 | 129 | 1 | 180 | 108 | 1 | ||
CT | 46 | 17 | 0.83(0.54–1.27) | 0.386 | 108 | 67 | 1.02(0.69–1.52) | 0.922 | ||
TT | 7 | 90 | 0.86(0.34–2.17) | 0.755 | 15 | 9 | 0.95(0.40–2.29) | 0.911 | ||
Dominant | CC | 90 | 198 | 1 | 180 | 108 | 1 | |||
CT + TT | 53 | 146 | 0.83(0.55–1.25) | 0.378 | 123 | 76 | 1.01(0.69–1.48) | 0.953 | ||
Recessive | CC + CT | 136 | 327 | 1 | 288 | 175 | 1 | |||
TT | 7 | 14 | 0.92(0.37–2.29) | 0.861 | 15 | 9 | 0.94(0.40–2.25) | 0.897 | ||
Log-additive | — | — | — | 0.87(0.62–1.22) | 0.427 | — | — | 1.00(0.73–1.38) | 0.999 |