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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Key m6A regulators mediated methylation modification pattern and immune infiltration characterization in hepatic ischemia-reperfusion injury

Fig. 5

Identification of m6A clusters as well as analysis of immune cell infiltration. A Matrix of consensus clustering of liver tissue samples 2 h after portal vein perfusion for k = 3. B The liver tissues 2 h after portal vein perfusion were divided into 3 clusters using consensus clustering (clusters A/B/C). A heat map was applied to show differential gene expressions of the three m6A gene clusters. C The 3 distinct m6A clusters were verified by PCA. D The expressions of METTL3, WTAP, RBM15, YTHDC1 and ALKBH5 were identified among the 3 m6A clusters. E Box plots showed the immune cells infiltrating in the 3 m6A clusters. *p < 0.05, **p < 0.01, ***p < 0.001; PCA, principal component analysis

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