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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Prognosis prediction based on methionine metabolism genes signature in gliomas

Fig. 1

Met metabolism genes expression is associated with clinical outcomes of gliomas. (A) Schematic of methionine metabolism pathways. MTA, 5′-methylthioadenosine; L-Met, L-methionine; SAM, S-adenosylmethionine; SAH, S-Adenosylhomocysteine; HCY, Homocysteine; Cys, Cysteine; Gln, Glutamine. (B, C) Clinical outcomes of glioma patients with low and high expression of methionine metabolism genes. Univariate clinical prognostic parameter analysis in TCGA databases. Abbreviations: CI, confidence interval; HR, hazard ratio (B); Kaplan-Meier survival analysis was performed in TCGA databases between low (blue) and high (red) expression levels (C). Survival differences were compared based on the division of the expression of methionine metabolism genes across the median into high and low

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