Fig. 5
From: Prognosis prediction based on methionine metabolism genes signature in gliomas
Functional annotation of Met metabolism gene signature. Gene set enrichment analysis (GSEA), Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis based on the differential genes between high and low-risk groups in TCGA (A, C, D) and CGGA325 (B, E, F). The gene sets with the highest enrichment scores were displayed. GO-BP: GO biological process analysis. (G, H) ESTIMATE/immune/stromal scores were significantly up-regulated in the high-risk groups in the TCGA and CGGA databases. ***, P < 0.001; Wilcoxon test. (I) TMB (tumor mutation burden) increased in the high-risk group, ***, P < 0.001; Wilcoxon test