Table 2 Putative target genes of the differentially expressed miRNAs in follicle fluid-derived exosomes in patients with DOR compared to normal control subjects. This table divides into three columns and nine rows, includes four items miRNA name, miRNA expression, and Genes, every row shows the differentially expressed miRNAs and their corresponding expression and predicted target genes

hsa-miR-483-3p

Up

RHOA, RAC1, IGF1, CDK4, BBC3, RASGRF1, SRF, CCNG1, SREBF1, PARD3, SMAD4, PRKAB1, EI24, CTGF, DLC1

hsa-miR-342-3p

Up

IKBKG, TAB2, TAB3, PDGFRA, SREBF2, CSF1, CCDC6, FOXJ3, BMP7, IGF1R, IRF1, GALNT10, MTDH, SREBF1, FUT8, CTBP2, ZDHHC9, DNMT1, ID4, BIRC6, E2F1

hsa-miR-625-3p

Up

PEG10, PAK2, MAP2K6

hsa-miR-675-3p

Up

SMAD1, SMAD5, IGF1R

hsa-miR-1246

Down

NFIB, GSK3B, AXIN2, DYRK1A, PRKAR1A

hsa-miR-122-5p

Down

MEF2D, ZNF395, CDK4, SOCS1, NT5C3A, P4HA1, PTPN1, CCNG1, DICER1, SPRY2, BCL2L2, FAM117B, DSTYK, PRKAB1, WNT1, IL1A, CTDNEP1, CREB1, LPIN1, PEG10, CYP7A1, PRKRA, FOXJ3, CCDC6, SLC7A11, TRIB1, EGLN3, NUMBL, ADAM17, AP3M2, SLC7A, FUT8, XPO6, UBAP2, TBX19, AACS, DUSP2, AXL, NOD2, ATP1A2, MAPK11, FUNDC2, AKT3, TPD52L2, ENTPD4, ANXA11, RHOA, RAB6B, FOXP1, RAC1, MECP2, GYS1, ANK2, NFATC2IP, SRF, IGF1R, GALNT10, PDK4, ADAM10, EGFR, VEGFC

hsa-miR-130b-3p

Down

UVRAG, PDGFRA, FMR1, CREB1, CSF1, CDK4, FOXJ3, MMP2, CCDC6, ZEB1, IRF1, EGLN3, TP53INP1, NKD2, CMPK1, DLL1, DICER1, PPARGC1A, SMAD4, CYLD, CYP2C9, BIRC6, E2F1, FOXP1, SMAD5, MECP2, IGF1, SNAI3, PPARA, ERBB2, SAV1, MST1, DSTYK, PRKAB1, RUNX3, WNT1, NFIB, ITGB1, DLC1, PTEN

hsa-miR-134-5p

Down

MAGI2, GOLPH3, CREB1, PUM2, NANOG, KRAS, FOXM1, TP53INP1, CCNG1, OPRM1, ANGPTL4, ZDHHC9, ABCC1, VEGFA, ERBB2, STAT5B, VIM, PAK2, ITGB1, RAB27A