Model | Genotype | DCM, n = 440 (%) | Controls, n = 532 (%) | OR (95% CI) | P value |
---|---|---|---|---|---|
rs10082466 | |||||
Codominant | A/A | 293 (66.6%) | 354 (66.5%) | 1.00 | |
G/A | 133 (30.2%) | 162 (30.4%) | 0.99 (0.75–1.31) | 0.986 | |
G/G | 14 (3.2%) | 16 (3.0%) | 1.06 (0.51–2.20) | ||
Dominant | A/A | 293 (66.6%) | 354 (66.5%) | 1.00 | 0.987 |
G/A- G/G | 147 (33.4%) | 178 (33.5%) | 1.00 (0.76–1.30) | ||
Recessive | A/A- G/A | 426 (96.8%) | 516 (97.0%) | 1.00 | 0.876 |
G/G | 14 (3.2%) | 16 (3.0%) | 1.06 (0.51–2.20) | ||
Overdominant | A/A- G/G | 307 (69.8%) | 370 (69.5%) | 1.00 | 0.940 |
G/A | 133 (30.2%) | 162 (30.4%) | 0.99 (0.75–1.30) | ||
Allele | A | 719 (82%) | 870 (82%) | 1.00 | 0.972 |
G | 161(18%) | 194 (18%) | 1.00 (0.79–1.26) | ||
rs2120132 | |||||
Codominant | T/T | 290 (65.9%) | 364 (68.4%) | 1.00 | |
C/T | 136 (30.9%) | 153 (28.8%) | 0.90 (0.68–1.18) | 0.703 | |
C/C | 14 (3.2%) | 15 (2.8%) | 0.85 (0.41–1.80) | ||
Dominant | T/T | 290 (65.9%) | 364 (68.4%) | 1.00 | 0.406 |
C/T- C/C | 150 (34.1%) | 168 (31.6%) | 0.89 (0.68–1.17) | ||
Recessive | T/T- C/T | 426 (96.8%) | 517 (97.2%) | 1.00 | 0.741 |
C/C | 14 (3.2%) | 15 (2.8%) | 0.88 (0.42–1.85) | ||
Overdominant | T/T- C/C | 304 (69.1%) | 379 (71.2%) | 1.00 | 0.465 |
C/T | 136(30.9%) | 153 (28.8%) | 0.90 (0.68–1.19) | ||
Allele | T | 716 (81%) | 881 (83%) | 1.00 | 0.410 |
C | 164(19%) | 183 (17%) | 0.91 (0.72–1.14) | ||
rs2099902 | |||||
Codominant | T/T | 235 (53.4%) | 289 (54.3%) | 1.00 | |
C/T | 176 (40.0%) | 211 (39.7%) | 1.03 (0.79–1.34) | 0.918 | |
C/C | 29 (6.6%) | 32 (6.0%) | 1.11 (0.66–1.90) | ||
Dominant | T/T | 235 (53.4%) | 289 (54.3%) | 1.00 | 0.776 |
C/T- C/C | 205 (46.6%) | 243 (45.7%) | 1.04 (0.81–1.34) | ||
Recessive | T/T- C/T | 411 (93.4%) | 500 (94%) | 1.00 | 0.713 |
C/C | 29 (6.6%) | 32 (6.0%) | 1.10 (0.66–1.85) | ||
Overdominant | T/T- C/C | 264 (60.0%) | 321 (60.3%) | 1.00 | 0.915 |
C/T | 176 (40.0%) | 211 (39.7%) | 1.01 (0.78–1.31) | ||
Allele | T | 646 (73%) | 789 (74%) | 1.00 | 0.710 |
C | 234 (27%) | 275 (26%) | 0.96 (0.79–1.18) | ||
rs7096206 | |||||
Codominant | C/C | 291 (66.1%) | 373 (70.1%) | 1.00 | |
C/G | 136 (30.9%) | 143 (26.9%) | 1.22 (0.92–1.61) | 0.383 | |
G/G | 13 (3.0%) | 16 (3.0%) | 1.04 (0.49–2.20) | ||
Dominant | C/C | 291 (66.1%) | 373 (70.1%) | 1.00 | 0.185 |
C/G- G/G | 149 (33.9%) | 159 (29.9%) | 1.20 (0.92–1.58) | ||
Recessive | C/C- C/G | 427 (97.0%) | 516 (97.0%) | 1.00 | 0.961 |
G/G | 13 (3.0%) | 16 (3.0%) | 0.98 (0.47–2.06) | ||
Overdominant | C/C- G/G | 304 (69.1%) | 389 (73.1%) | 1.00 | 0.167 |
C/G | 136 (30.9%) | 143 (26.9%) | 1.22 (0.92–1.61) | ||
Allele | C | 718 (82%) | 889 (84%) | 1.00 | 0.255 |
G | 162 (18%) | 175(16%) | 0.87 (0.69–1.10) | ||
rs11003125 | |||||
Codominant | G/G | 133 (30.2%) | 115 (21.6%) | 1.00 | |
C/G | 220 (50.0%) | 288 (54.1%) | 0.66 (0.49–0.90) | 0.007* | |
C/C | 87 (19.8%) | 129 (24.2%) | 0.58 (0.40–0.84) | ||
Dominant | G/G | 133 (30.2%) | 115 (21.6%) | 1.00 | 0.002* |
C/G- C/C | 307 (69.8%) | 417 (78.4%) | 0.64 (0.48–0.85) | ||
Recessive | G/G- C/G | 353 (80.2%) | 403 (75.8%) | 1.00 | 0.094 |
C/C | 87 (19.8%) | 129 (24.2%) | 0.77 (0.57–1.05) | ||
Overdominant | G/G- C/C | 220 (50.0%) | 244 (45.9%) | 1.00 | 0.199 |
C/G | 220 (50.0%) | 288 (54.1%) | 0.85 (0.66–1.09) | ||
Allele | G | 486 (55%) | 518 (49%) | 1.00 | 0.003* |
C | 394 (45%) | 546 (51%) | 0.76 (0.63–0.91) |