Table 3 Comparisons of clinical features among different genotypes of the NLRP3 gene polymorphisms among the included COM patients

Age Median

(IQR)

46 (30.5, 58)

48 35.5, 59)

48 (33, 60)

0.747

52.5 (32.5, 70)

43 (31, 59)

48 (34.5, 59)

0.583

NA

59 (27, 59)

47 (33, 59)

0.616

48.5 (38.5, 59.25)

45 (32, 59)

48 (32.5, 61.75)

0.193

Sex ratio (M/F)

4.65

2.95

2.94

0.210

7.00

4.15

3.12

0.455

NA

NA

3.33

0.344

2.69

3.29

5.13

0.176

PTOM proportion (%)(PTOM/COM)

46.76

56.47

54.39

0.593

37.50

75.47

72.29

0.575

NA

66.67

72.64

0.647

66.67

75.45

72.22

0.789

Positive rate of culture (%)

40.30

32.80

32.20

0.553

37.50

42.10

32.80

0.302

NA

66.70

35.10

0.545

30.40

33.60

45.10

0.148

Polymicrobial infection (%)

16.50

15.10

13.80

0.645

25.00

18.70

14.00

0.580

NA

33.30

15.30

0.724

17.40

14.30

15.40

0.454

IL-6 (pg/ml) Median (IQR)

7.33 (2.87,16.57)

5.87

(3.18,

12.70)

7.83

(4,58,

16.12)

0.213

9.53

(1.65,

12.18)

7.10

(2.99,

16.20)

6.36

(3.20,

14.63)

0.900

NA

9.31

(6.01,

9.31)

6.54

(3.17,

14.79)

0.250

6.07

(3.34,

12.37)

6.64

(3.26,

15.08)

6.17

(2.50,

16.76)

0.939

TNF-α (pg/ml) Median (IQR)

8.92

(6.75,

11.88)

9.08

(6.87,

12.33)

8.34

(7.15,

10.30)

0.662

8.66

(7.25,

13.51)

9.30

(6.79,

11.83)

8.81

(6.84,

11.90)

0.843

NA

7.88

(6.15,

7.88)

8.98

(6.87,

11.90)

0.978

8.34

(6.81,

12.80)

9.04

(7.07,

11.65)

8.84

(6.39,

12.30)

0.972