Skip to main content
Fig. 1 | BMC Medical Genomics

Fig. 1

From: Broadening the phenotype and genotype spectrum of novel mutations in pontocerebellar hypoplasia with a comprehensive molecular literature review

Fig. 1

Schematic representation of main pathways involved in PCH. a schematic representation of tRNA splicing by TSEN complex and CLP1. b charging of Arg-related tRNA by RARS2. c) the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA by SepSecs. d) exosome complex: the structural cap including EXOSC1-3, the core ring including EXOSC4-9, and the catalytic unit made up of DIS3 protein. e) Processing of immature 3’-tailed human telomerase RNA component (hTR) to mature 451nt hTR. f) structure of the human spliceosome prior to exon ligation. PRP17 and PPIL1 are shown by arrows

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us