Preliminary study of the effect of gut microbiota on the development of prostatitis

BMC Medical Genomics

Table 2 MR estimates for the relationship between genetically instrumented gut microbiota and Prostatitis

Classification		nSNP	SE	P-value	OR (95% CI)	Pleiotropy			Heterogeneity		MR-PRESSO
Classification		nSNP	SE	P-value	OR (95% CI)	Egger intercept	SE	P-value	Q	P-value	MR-PRESSO
Category
class	Methanobacteria.id.119	9	0.108	0.001	0.692(0.560–0.855)	-0.038	0.068	0.586	4.709	0.788	0.586
family	Methanobacteriaceae.id.121	9	0,108	0.001	0.692(0.560–0.855)	-0.039	0.067	0.586	4.709	0.788	0.586
Genus	Erysipelatoclostridium.id.11,381	15	0.132	0.011	0.714(0.551–0.925)	-0.027	0.042	0.536	14.871	0.387	0.536
	Faecalibacterium.id.2057	10	0.196	0.018	1.591 (1.082–2.340)	0.026	0.055	0.641	11.099	0.435	0.15
·
	LachnospiraceaeUCG004.id.11,324	12	0.183	0.007	1.639 (1.147–2.343)	0.039	0.048	0.440	7.332	0.711	0.440
	Parasutterella.id.2892	14	0.132	0.023	0.740 (0.571–0.959)	0.003	0.029	0.925	7.144	0.894	0.915
	Slackia.id.825	6	0.170	0.030	0.690 (0.494–0.964)	0.151	0.109	0.239	3.443	0.631	0.239
	Sutterella.id.2896	12	0.168	0.007	1.578 (1.135–2.194)	-0.058	0.048	0.257	7.601	0.748	0.257
Order	Gastranaerophilales.id.1591	9	0.147	0.008	1.476 (1.104–1.972)	-0.020	0.053	0.71	10.164	0.253	0.711

MR-PRESSO, Mendelian randomization pleiotropy residual sum and outlier; SNPs, single nucleotide polymorphisms; CI, confidence interval; OR, odds ratio; Q, heterogeneity statistic Q; SE, Standard Error;

ISSN: 1755-8794