Fig. 1
From: Integrated analysis identifies GABRB3 as a biomarker in prostate cancer
Manhattan plots depict the relationships (Y-axis as − log10(P) values) between 399 single-nucleotide polymorphisms (X-axis as their positions on chromosomes) located within 28 PI3K/AKT pathway genes and progression-free survival (A), overall survival (B), and cancer-specific survival (C) of patients with prostate cancer undergoing androgen-deprivation therapy. The nominal significance threshold (P = 0.05) is represented by a dashed horizontal line and genes exhibiting noteworthy relationships are indicated