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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Quantified pathway mutations associate epithelial-mesenchymal transition and immune escape with poor prognosis and immunotherapy resistance of head and neck squamous cell carcinoma

Fig. 3

Multi-omics differences in IWHMB-associated cancer clusters in TCGA cohort. A Circular cluster dendrogram showing 12 IWHMB-associated cancer clusters. B Heatmap showing 12 IWHMB-associated cancer clusters. C Clinical prognosis of 12 IWHMB-associated cancer clusters. D Somatic mutation waterfall plot of 12 IWHMB-associated cancer clusters. (E) Differential copy number changes (Fisher's precision probability test pvalue < 0.05) in 12 IWHMB-associated cancer clusters. F TMB of 12 IWHMB-associated cancer clusters. G CNV Burden of 12 IWHMB-associated cancer clusters. H-J StromalScore, TumorPurity and ImmuneScore of 12 IWHMB-associated cancer clusters. K Relationship between IWHMB- associated cancer clusters and Kech clusin of 12 IWHMB-associated cancer clusters. L DEGs of 12 IWHMB-associated cancer subtypes. M GSEA pathway enrichment of 12 IWHMB-associated cancer subtypes. N GSEA-enriched pathways shared by 6 IWHMB-related cancer clusters in two HNSCC cohorts. O Shared genomic features of 9 IWHMB-related cancer clusters in two HNSCC cohorts

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BMC Medical Genomics

ISSN: 1755-8794

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