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Fig. 8 | BMC Medical Genomics

Fig. 8

From: Quantified pathway mutations associate epithelial-mesenchymal transition and immune escape with poor prognosis and immunotherapy resistance of head and neck squamous cell carcinoma

Fig. 8

Identification and analysis of BHG (A) Identification of Driver HGS. B Proportion of different cancer Hot genes in BHG. C Bayesian network visualization of 4 cancer driver pathways enriched in BHG. D Forest plots showing the top 15 genes with significant pvalue for BHG in the Cox model at 3 omics levels. E GSEA analysis of BHGs in 6 ICI cohorts (response vs. resistant)

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