Fig. 9

Comparison of BHG and other predictive gene signatures in multiple ICI cohorts (A) Overview of the BHG-based ICI prediction model. B AUC values for predicting ICI responses in the Braun et al. (2020) cohort by combining 6 machine learning models based on 3 omics of BHG. C Comparison of AUC means of BHG with 10 and 70 gene signatures in multiple ICI cohorts for predicting ICI response at the somatic mutation and gene expression levels, respectively