Table 5 HLA class I (A, B) and class II (DRB1, DQB1) two-loci haplotypes with significant linkage disequilibrium (P < 0.05 in all cases) in Central Tunisians
HLA | Haplotype | Haplotype Frequency (HF) | D’ | HLA | Haplotype | Haplotype Frequency (HF) | D’ |
|---|---|---|---|---|---|---|---|
A,B (2n = 544) | 02 58 | 0.0165 | 1.000 | DRB1-DQB1 (2n = 348) | 13 03 | 0.0402 | 0.639 |
02 51 | 0.0477 | 1.000 | 04 03 | 0.1063 | 0.659 | ||
30 13 | 0.0220 | 0.977 | 07 03 | 0.0287 | 1.000 | ||
02 18 | 0.0257 | 0.976 | 13 06 | 0.0603 | 0.971 | ||
01 07 | 0.0202 | 1.000 | 07 02 | 0.1494 | 0.999 | ||
03 50 | 0.0238 | 1.000 | 11 05 | 0.0114 | 0.993 | ||
03 35 | 0.0147 | 0.527 | 11 03 | 0.1178 | 1.000 | ||
30 50 | 0.0183 | 0.706 | 15 06 | 0.1034 | 1.000 | ||
01 57 | 0.0165 | 0.809 | 10 05 | 0.0201 | 0.999 | ||
02 49 | 0.0183 | 0.618 | 14 05 | 0.0114 | 0.995 | ||
02 50 | 0.0441 | 1.000 | 12 03 | 0.0114 | 1.000 | ||
30 44 | 0.0165 | 0.689 | 01 05 | 0.0545 | 1.000 | ||
02 44 | 0.0165 | 0.683 | 08 04 | 0.0201 | 1.000 | ||
23 44 | 0.0238 | 0.668 | 16 05 | 0.0143 | 0.997 | ||
23 50 | 0.0202 | 0.926 | 03 04 | 0.0114 | 0.713 | ||
DRB1-DQB1 (2n = 348) | 04 04 | 0.0448 | 0.982 |  | |||
03 02 | 0.1178 | 0.982 | |||||
08 06 | 0.0258 | 0.639 | |||||