Fig. 10
From: Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis
SGOL1 promoted ccRCC cell migration and invasion. A A wound healing assay was conducted to assess the migration of 786-O and SW839 cells. B GSEA results of “hallmark epithelial–mesenchymal transition” enrichment in the high-SGOL1-expression group. C Representative images of Transwell migration and invasion in SGOL1-KD 786-O cells and SGOL1-OE SW839 cells. n = 5, Scale bar = 100 μm. The results of the quantitative analysis are shown as mean ± SD on the right. D The protein expression of p21, Cyclin D1, Cyclin E1, CDK2, E-cadherin, N-cadherin, MMP2, and MMP9 in SGOL1-KD 786-O cells and SGOL1-OE SW839 cells was assessed via western blotting. (**P < 0.01, ***P < 0.001)