Fig. 7

SGOL1 was found to be potentially targeted by miR-23b-3p in ccRCC. A Five potential binding miRNAs targeting SGOL1 based on the GSCA database. B Correlation analysis between the five candidate miRNAs and SGOL1 expression in ccRCC. The R-value represents the Spearman correlation coefficient. C Comparison of miR-23b-3p expression between ccRCC tissues and peritumoral normal tissues (Normal = 71, Tumor = 545). D Survival analysis (OS, DSS, and PFI) confirmed that miR-23b-3p upregulation was correlated with favorable survival in ccRCC patients. (E) Bubble plot of the correlation between the expression of miR-23b-3p and 24 types of immune cells in ccRCC. (F) Correlation analysis of miR-23b-3p expression and Treg cell infiltration by box and scatter plots (Low = 270, High = 271). (***P < 0.001)