Table 5 Comparison of the variant frequencies of SLC26A4 c.919-2A > G and c.2168 A > G among Han Chinese and Ethnic minority patients with NSHL in China
Author Reference | Han Chinese patients (n) | Ethnic minority patients (n) | ||||
|---|---|---|---|---|---|---|
Region/area | Han Chinese patients / Minority patients (n) | c.919-2A > G, No. of allele, frequency (%) | c.2168 A > G, No. of allele, frequency (%) | c.919-2A > G, No. of allele, frequency (%) | c.2168 A > G, No. of allele, frequency (%) | |
in this paper | Southwestern China’s Yunnan | 533 / 634 | 29 (2.72%) | 5 (0.47%) | 12 (0.95%) | 4 (0.32%) |
Duan et al., 2015 [37] | Northwester China’s Ningxia, Qinghai | 234 / 250 | 28(5.98%) | 14(2.99%) | 24(4.80%) | 8 (1.60%) |
Du et al., 2014 [38] | Northwester China’s Gansu | 1809 / 515 | 386 (10.67%) | 112 (3.10%) | 52 (5.05%) | 27 (2.62%) |
Chen et al., 2011 [39] | Northwester China’s Xinjiang | 151 / 199 | 25 (8.28%) | 5 (1.66%) | 5 (1.26%) | 2 (0.50%) |
Dai et al., 2008 [13] | China/27 regions | 2783 / 465 | 533 (9.58%) | —— | 29 (3.12%) | —— |