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Fig. 6 | BMC Medical Genomics

Fig. 6

From: GPX8+ cancer-associated fibroblast, as a cancer-promoting factor in lung adenocarcinoma, is related to the immunosuppressive microenvironment

Fig. 6

Clinical value of GPX8. A Heatmap of GPX8 correlation with immune checkpoints in 3 LUAD cohorts. B Distribution of GPX8 expression in immune-responsive and non-immune-responsive groups assessed based on the TIDE algorithm. C Correlation scatter plots of GPX8 with TIDE scores in the 3 LUAD cohorts. D Differential gene volcano plot based on high and low GPX8 expression groups. E Venn plots showing up- and down-regulated genes shared in the 3 cohorts (adj. p value < 0.05 and |logFC| > 1). F Small molecule drugs screened based on up- and down-regulated genes and the cMAP database, with the heatmap at the top ranking the small molecules

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BMC Medical Genomics

ISSN: 1755-8794

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