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Table 6 CYP4A22 SNP–SNP interaction models analyzed by the MDR method

From: Novel polymorphisms in CYP4A22 associated with susceptibility to coronary heart disease

Model

Training Bal. Acc

Testing Bal. Acc

OR (95% CI)

p-value

CVC

rs2056900

0.533

0.526

1.42 (1.13–1.78)

0.0027

9/10

rs76011927, rs2056900

0.539

0.507

1.44 (1.14–1.80)

0.0018

7/10

rs76011927, rs12564525, rs2056900

0.543

0.510

1.48 (1.18–1.86)

0.0007

6/10

rs76011927, rs12564525, rs2056900, rs4926581

0.546

0.513

1.61 (1.28–2.02)

< 0.0001

10/10

  1. MDR, multifactor dimensionality reduction; Bal. Acc., balanced accuracy; CVC, cross-validation consistency; OR, odds ratio; 95% CI, 95% confidence interval
  2. p values were calculated using χ2 tests; ‘p-value < 0.05’ and bold text represent statistical significance
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BMC Medical Genomics

ISSN: 1755-8794

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