Table 3 Correlation between clinical features and number of genes lost in NF1 deletion (excluding Patient 2 with deletion > 5.5 Mb)

Overall Severity of NF

Mild/moderate

N = 9

33 (25–37)

0.3435

Severe

N = 12

33 (26–37)

Plexiform neurofibromas

No

N = 7

33 (26–33)

0.0632

Yes

N = 11

33 (26–37)

Lisch Nodules

No

N = 4

33 (32–36)

0.7915

Yes

N = 9

33 (25–37)

Macrocephaly

No

N = 5

33 (32–36)

0.4515

Yes

N = 9

33 (26–33)

Learning Difficulties

No

N = 2

26 (26–26)

0.0087

Yes

N = 15

33 (32–37)

Scoliosis

No

N = 13

33 (26–37)

0.5146

Yes

N = 5

33 (32–33)

Other Malignancies

No

N = 16

33 (26–37)

0.8725

Yes

N = 4

33 (32–37)