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Table 3 Characters of 28 candidate risk factors in European ancestry

From: Peripheral blood indicators and COVID-19: an observational and bidirectional Mendelian randomization study

Category

Phenotype_name

Abbreviation

GWAS id

Sample Size

N_SNPs

F

Hematological traits

White blood cell (leukocyte) count

WBC

ieu-b-30

563,946

507

107.69

Basophil cell count

BASO

ieu-b-29

563,946

201

109.61

Lymphocyte cell count

LYM

ieu-b-32

563,946

510

113.99

Eosinophil cell count

EOS

ieu-b-33

563,947

448

140.17

Neutrophil count

NEU

ukb-d-30140_irnt

349,856

296

87.90

Red blood cell count

RBC

ukb-d-30010_irnt

350,475

358

79.17

Hemoglobin concentration

HGB

ukb-d-30020_irnt

350,474

301

56.93

Hematocrit

HCT

ebi-a-GCST90002304

562,259

463

101.22

Mean platelet (thrombocyte) volume

MPV

ukb-d-30100_irnt

350,470

440

251.48

Plateletcrit

PCT

ebi-a-GCST004607

164,339

227

98.83

Platelet distribution width

PDW

ukb-d-30110_irnt

350,470

350

177.40

D-dimer

DD

prot-a-1086

3,301

12

24.66

Hepatic and renal function markers

Alkaline phosphatase

ALP

ukb-d-30610_raw

344292

252

48848.18

Albumin

ALB

ukb-d-30600_raw

315,268

201

525.67

Total bilirubin

Tbil

ukb-d-30840_raw

342829

89

3594.81

Myocardial injury markers

Myoglobin levels

MB

ebi-a-GCST90012047

21,758

25

28.51

Troponin I, cardiac muscle

Tnl

prot-a-3066

3,301

9

24.18

Creatine kinase B-type

CKB

prot-a-565

3,301

17

24.81

Creatine kinase M-type

CKM

prot-a-566

3,301

3

46.67

Metabolic indexes

HDL cholesterol

HDLC

ieu-b-109

403,943

362

112.33

Total cholesterol

TC

met-d-Total_C

115,078

64

130.66

apolipoprotein A-I

ApoA

ieu-b-107

393,193

299

112.57

Hemoglobin A1c

HbA1c

ukb-d-30750_raw

344,182

190

4703.55

Inflammatory parameters

C-Reactive protein

CRP

ukb-d-30710_raw

343,524

53

2842.86

Serum amyloid A-1 protein

SAA

prot-a-2623

3301

15

139.63