Fig. 3

Characterization of the breakpoints of the DPYD deletion. A Schematic illustration of part of the DPYD transcript variant NM_000110.4. Exons are represented by rectangles and intervening introns by lines. Red arrows denote the position of the breakpoints. B Nucleotide sequence, upstream and downstream of each breakpoint. The deleted sequence is indicated in blue letters. C Sequencing electropherogram of the patient at the junction region